2F-Ketamine (2-FDCK): mode of action, effects and dosage

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2F-Ketamine, 2-FDCK or 2-Fluorodeschloroketamine is a dissociative anaesthetic related to ketamine and is a dissociative substance from the class of arylcycohexylamine. 2-FDCK is closely related to ketamine and its effects are therefore similar.

2-FDCK operation

To properly understand the subjective effects of 2-FDCK, it is important to know its chemical structure. The full chemical name of 2-FDCK is 2-(2-Fluorophenyl)-2-methylamino-cyclohexanone. Like all substances in the class (arylcycohexylamines), 2-FDCK has a cyclohexane ring bound to an aromatic ring together with an amino group. It also contains a phenyl ring bound to the cyclohexane ring.

However, there is one major distinction between 2F-Ketamine and ketamine, which is that 2-FDCK contains a fluorine atom attached to the phenyl group, while ketamine contains a chlorine atom. Like most substances in the arylcycohexylamine class, 2-FDCK is expected to act mainly by antagonising NMDA receptors. By antagonising our NMDA receptors, it is likely to cause feelings of anaesthesia and dissociation, as well as hallucinogenic side effects.

2-FDCK operation

2-FDCK experience

Order 2-FDCK? Since the chemical structure of 2-FDCK is similar to that of ketamine, the effects of 2F-Ketamine are also similar to those of ketamine. The most prominent effects of 2-FDCK are dissociation, psychological suppression, disinhibition and hallucinations. Many users have described the effects of 2-FDCK as an overall suppression of emotions, sense of self and cognitive ability.

At higher doses, online trip reports report a feeling of consciousness detaching from the body. There are reports that 2-FDCK is a "k-hole" can cause when using very large doses. A k-hole is when high doses of the substance start causing intense feelings of dissociation. This can cause feelings of being disconnected from or unable to control one's own body, sometimes also losing the ability to speak and move.

2-FDCK dosage

Like ketamine, 2-FDCK is difficult to dose. According to online reports, a 2-FDCK dose is comparable to that of its better-known sibling ketamine, yet 2-FDCK is 15 to 25 per cent stronger than ketamine. It is recommended anyway to start with a low dose, meaning less than 25 mg. The first effects are noticeable after a few minutes to 15 minutes. The effects last 1 to 4 hours, but even after that they may be visible in a brain scan.

Hallucinations and "seeing music" are certainly not uncommon. 2-FDCK users, when using 2-FDCK, report an increase in the absorption of external stimuli, be it music, TV or anything else. At higher doses, this can even lead to thinking you are a part of the film or music and no longer being able to distinguish between, say, the television screen and the real world.

2F-Ketamine or ketamine?

The chemical structure of 2-FDCK differs from ketamine only in that it has a fluorine atom attached to the phenyl group. Ketamine has a chlorine atom in that place instead. 2F-Ketamine or 2FDCK is considered a legal alternative to ketamine, but since it can really only be used as a research chemical, this is not entirely correct.

2F-Ketamine has been an incredibly popular dissociative drug since its introduction on the market in 2017 and since then. According to 2-FDCK trip reports, 2-FDCK has a longer effect than ketamine, which is a big reason for its popularity. However, this can also be a disadvantage if you prefer to feel "normal" again at some point.

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